The Colección Cisneros is a visual arts program of the Fundación Cisneros. Its mission is to collect, preserve, study, and exhibit the Colección’s extensive artworks and related archives, which consist primarily of modern and contemporary art, with an emphasis on Latin America. The Colección also includes Colonial Latin American art, international decorative arts, and a selection of Latin American landscapes from the seventeenth to the early twentieth century, executed by both local artists and those who traveled to the continent from North America and Europe. Through exhibitions, a dynamic lending program, publications, arts education programs, and online access, the program works to heighten the appreciation of the diversity, quality, and range of art from Latin America.

The Colección supports arts education in Caracas schools through the Programa de Pensamiento Visual (PPV). Developed by The Museum of Modern Art in New York (MoMA) and adapted for Venezuelan schoolchildren with the help of educators from MoMA and The Galería de Arte Nacional in Caracas, PPV uses artworks from all three collections to help children develop critical visual-thinking skills.

In an effort to broaden awareness of Latin American art at the curatorial level, the Patricia Cisneros Travel Fund for Latin America enables curators from MoMA to travel to Latin America. In addition, in 1999, the Fundación Cisneros created The Cisneros Fellowship, supporting Latin American students in the two-year post-graduate curatorial studies course at Bard College in New York.

The Colección also publishes a series of catalogues and books that highlight aspects of the Colección and Latin American art and are distributed throughout Latin America and the United States.